Peer-reviewed veterinary case report
Major prospects for exploring canine vector borne diseases and novel intervention methods using 'omic technologies.
- Journal:
- Parasites & vectors
- Year:
- 2011
- Authors:
- Gasser, Robin B et al.
- Affiliation:
- Department of Veterinary Science · Australia
- Species:
- dog
Plain-English summary
Canine vector-borne diseases (CVBDs) are illnesses that dogs can get from parasites like ticks and mosquitoes, and they are a big concern for pet owners around the world. While there has been some research on these diseases, scientists haven't fully explored the tiny details of the germs that cause them, the bugs that spread them, and how these germs interact with dogs or resist treatments. This article discusses how new technologies, like advanced genetic testing and data analysis, could help researchers understand these diseases better and develop new ways to prevent and treat them. By using these innovative methods, we may find more effective strategies to manage and combat CVBDs in dogs.
Abstract
Canine vector-borne diseases (CVBDs) are of major socioeconomic importance worldwide. Although many studies have provided insights into CVBDs, there has been limited exploration of fundamental molecular aspects of most pathogens, their vectors, pathogen-host relationships and disease and drug resistance using advanced, 'omic technologies. The aim of the present article is to take a prospective view of the impact that next-generation, 'omics technologies could have, with an emphasis on describing the principles of transcriptomic/genomic sequencing as well as bioinformatic technologies and their implications in both fundamental and applied areas of CVBD research. Tackling key biological questions employing these technologies will provide a 'systems biology' context and could lead to radically new intervention and management strategies against CVBDs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21489242/