Peer-reviewed veterinary case report
Malignant fibrous histiocytoma in dogs and cats.
- Journal:
- Veterinary pathology
- Year:
- 1979
- Authors:
- Gleiser, C A et al.
Plain-English summary
Researchers studied five soft tissue tumors in dogs and cats, identifying them as malignant fibrous histiocytomas, which are a type of cancer made up of certain immune cells and connective tissue cells. The tumors had different appearances, and three of them included large cells with multiple nuclei, a variant that was only found in cats. These tumors in pets are similar to those seen in humans, sharing characteristics in the way the cancerous cells look and behave. This information can help veterinarians better understand and treat these types of tumors in pets.
Abstract
Five soft tissue tumors of varied morphology in dogs and cats were classified as malignant fibrous histiocytomas on the basis of their histologic composition. All were composed of varying mixtures of histiocytes and fibroblasts and three contained large multinucleated cells. This giant cell variant of malignant fibrous histiocytoma was seen only in cats. These tumors are comparable to those described in man as malignant fibrous histiocytoma on the basis of the malignant histiocyte and its varied morphology and function.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/220777/