Peer-reviewed veterinary case report
Malignant glomus tumor found in German shepherd dog
By Park, Chun-Ho et al.·Published in Veterinary dermatology·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Malignant glomus tumour in a German shepherd dog.
- Species:
- dog
Plain-English summary
An 8-year-old male German shepherd was found to have a 2.5 cm mass near his hip that was not encapsulated and showed signs of bleeding. After the mass was surgically removed, it was diagnosed as a malignant glomus tumor, which is a type of cancer that can occur in soft tissues. The tumor was made up of abnormal cells and blood vessels, indicating it was aggressive. Treatment involved surgical removal, and while the outcome isn't specified, early detection and removal are crucial for better prognosis in such cases.
People also search for: German shepherd tumor treatment · dog cancer symptoms · malignant glomus tumor in dogs
Abstract
A solitary mass, 2.5 cm x 2.5 cm x 2.0 cm in size, was found in the subcutis adjacent to the ischial tuberosity of an 8-year-old male German shepherd dog. The excised mass was not encapsulated and the cut surface was solid, grey-white and had multiple red areas suggestive of haemorrhage. Microscopically, the neoplasm was composed of epithelioid cells interspersed with venous vessels of various sizes and irregular bundles of spindle-shaped tumour cells with mucinous stroma. The nuclei showed anisokaryosis and many mitotic figures were noted. Immunohistochemically, the majority of tumour cells were positive for alpha smooth-muscle actin and vimentin, but negative for cytokeratin, desmin, S-100 and factor VIII-related antigen. Ultrastructurally, the tumour cells contained irregular nuclei, few mitochondria, few rough endoplasmic reticulum, cytoplasmic myofilaments of intermediate density, pinocytotic vesicles and distinct basal lamina. Based on these pathological findings, the diagnosis was malignant glomus tumour.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19220826/