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Peer-reviewed veterinary case report

Malignant histiocytosis causing severe anemia in a 13-year-old cat

By Court, E A et al.·Published in Journal of the American Veterinary Medical Association·1993·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Malignant histiocytosis in a cat.

Species:
cat
Feline leishmaniasisStomach & digestionCats

Plain-English summary

A 13-year-old male domestic shorthair cat was brought in with severe anemia and other blood issues, which made him very weak. Despite receiving blood transfusions, his condition did not improve, and he remained critically low in red blood cells. Sadly, the decision was made to euthanize him, and a post-mortem examination revealed that his organs were affected by malignant histiocytes, which are abnormal immune cells that can cause serious health problems.

People also search for: cat anemia symptoms · why is my cat weak · malignant histiocytosis in cats · cat blood transfusion failure · elderly cat health issues

Abstract

A 13-year-old male domestic shorthair cat was found to have normocytic hypochromic regenerative anemia, lymphopenia, eosinopenia, thrombocytopenia, hyperglycemia, hyperbilirubinemia, and a prolonged activated partial thromboplastin time. Transfusions of packed RBC failed to maintain the PCV above 13% for > 8 hours. The cat was euthanatized. At necropsy, the spleen liver, lymph nodes, and bone marrow were infiltrated with malignant histiocytes undergoing erythrophagocytosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8253623/