Peer-reviewed veterinary case report
Malignant testicular tumor causing scrotal swelling in a dog
By Vascellari, Marta et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2011·Histopathology Department, Italy·View original on PubMed →
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Original publication title: Malignant mesothelioma of the tunica vaginalis testis in a dog: histological and immunohistochemical characterization.
- Species:
- dog
Plain-English summary
A 9-year-old male mixed-breed dog was brought in with a large swelling in the scrotum. An ultrasound revealed an irregular mass in the left testicle's vaginal canal. After examining tissue samples, the vet diagnosed the dog with a rare type of cancer called malignant mesothelioma. Unfortunately, this type of cancer is aggressive and not commonly seen in dogs. Treatment options may vary, but the prognosis can be serious due to the nature of the disease.
People also search for: dog scrotal swelling · testicular cancer in dogs · malignant mesothelioma treatment for dogs
Abstract
Histologic and immunohistochemical features of a malignant mesothelioma of the testicular tunica vaginalis in a 9-year-old male mixed-breed dog are reported. The dog had a large scrotal swelling determined by ultrasonography to be a heterogeneous irregular mass characterized by a mixed echogenic pattern and located in the left vaginal canal of the testis. Histologically, the neoplasm was nodular, was poorly demarcated, and consisted of pleomorphic cells that were associated with a significant desmoplastic reaction. By immunohistochemistry, neoplastic cells stained positively for cytokeratin and vimentin and were immunoreactive with an antimesothelial cell monoclonal antibody. Malignant mesotheliomas of tunica vaginalis testis are rare in mammalian species, including dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21217045/