Peer-reviewed veterinary case report
Malignant nerve tumor found in a dog's kidney
By Nam, Da-Ye et al.·Published in The Journal of veterinary medical science·2024·College of Veterinary Medicine and Veterinary Medical Research Institute, South Korea·View original on PubMed →
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Original publication title: Malignant peripheral nerve sheath tumor in the kidney of a dog.
- Species:
- dog
Plain-English summary
A 12-year-old male poodle was brought to the vet because he was vomiting and had diarrhea. After running tests like ultrasound and CT scans, the vet found a mass on the left kidney that was about the size of a small egg. The mass was diagnosed as a malignant peripheral nerve sheath tumor, which is a type of cancer that can invade nearby tissues. This case is notable because it’s the first time this kind of tumor has been reported in a dog's kidney. Unfortunately, the prognosis for this type of cancer can be serious, and treatment options would need to be discussed with a veterinarian.
People also search for: dog vomiting and diarrhea · poodle kidney tumor · malignant nerve sheath tumor in dogs
Abstract
A 12-year-old castrated male poodle presented with vomiting and diarrhea. Ultrasonography and computed tomography revealed a protruding mass at the caudal pole of the left kidney. Grossly, the poorly circumscribed abnormal mass was 1.6 × 1.8 × 1.9 cm in size and had multifocal dark-red foci. Microscopically, it was composed of densely or loosely packed variable-sized short spindle or ovoid cells. These neoplastic cells showed high pleomorphism, mitotic figures, and invasive tendency to the adjacent tissue. Immunohistochemically, the neoplastic spindle cells expressed vimentin, S100, neuron-specific enolase, nerve growth factor receptor, and laminin. Therefore, the mass was diagnosed as a malignant peripheral nerve sheath tumor (MPNST). To our knowledge, this is the first report of primary renal MPNST in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38296525/