Peer-reviewed veterinary case report
Dog with large malignant nerve tumor in liver causing belly pain
By Park, J-W et al.·Published in Journal of comparative pathology·2011·Department of Veterinary Pathology, South Korea·View original on PubMed →
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Original publication title: Malignant peripheral nerve sheath tumour in the liver of a dog.
- Species:
- dog
Plain-English summary
A 14-year-old male mixed breed dog was brought in due to a swollen belly and pain in the abdomen. X-rays showed a large mass in the liver, which was later confirmed to be a malignant peripheral nerve sheath tumor after a thorough examination. This type of tumor is rare in dogs, especially in the liver. Unfortunately, the dog’s condition was serious due to the size of the tumor, and it was not able to recover.
People also search for: dog abdominal swelling · liver tumor in dogs · malignant peripheral nerve sheath tumor in dogs
Abstract
A 14-year-old male mixed breed dog was presented for abdominal distension and abdominal pain. Radiographical examination identified a large space-occupying mass in the abdomen. Necropsy examination revealed the presence of a 12cm hepatic mass that occupied almost half of the abdominal cavity. Microscopically, this mass consisted of spindle-shaped neoplastic cells that were arranged in short streams and interlacing bundles. Immunohistochemically, the neoplastic cells expressed vimentin, S-100, protein gene product 9.5 and neuron specific enolase, but were negative for cytokeratin, smooth muscle actin, melan A and von Willebrand Factor. These findings indicated that the hepatic mass was a primary hepatic peripheral nerve sheath tumour. To our knowledge, this is the first documentation of a primary hepatic malignant peripheral nerve sheath tumour in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20875645/