Peer-reviewed veterinary case report
Malignant nerve tumor found in a dog's urinary bladder
By Lee, S-W et al.·Published in Journal of comparative pathology·2020·Department of Veterinary Pathology, South Korea·View original on PubMed →
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Original publication title: Malignant Peripheral Nerve Sheath Tumour in the Urinary Bladder of a Dog.
- Species:
- dog
Plain-English summary
A 15-year-old neutered male miniature pinscher was brought to the vet with a growth in its urinary bladder. During surgery, the vet found a 4 cm mass that was attached to the bladder wall and was causing issues. Tests showed that the mass was a malignant peripheral nerve sheath tumor, which is a type of cancer. This case is notable because it’s the first time such a tumor has been reported in a dog's bladder. Unfortunately, the outcome of the treatment is not mentioned, so it's unclear how the dog fared after surgery.
People also search for: dog bladder tumor symptoms · miniature pinscher cancer treatment · urinary bladder mass in dogs
Abstract
A 15-year-old neutered male miniature pinscher was presented with a pedunculated mass (4 × 1 cm) in its urinary bladder. Exploratory cystotomy revealed that the mass was located at the trigone of the bladder and projected into the lumen. The cut surface of the mass was homogeneous grey to tan in colour with focal brown pigmentation. Microscopically, the mass was predominantly composed of neoplastic spindle cells characterized by moderate cellular pleomorphism, invasion into the muscular layer of the bladder wall and few mitotic figures. The neoplastic spindle cells formed interwoven bundles intersecting at various angles. Immunohistochemically, these cells were negative for cytokeratin 7 and α-smooth muscle actin, but strongly expressed S100 and vimentin, confirming a diagnosis of a malignant peripheral nerve sheath tumour (PNST). To the best of our knowledge, this is the first report of a primary malignant PNST in the urinary bladder of a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32138844/