Peer-reviewed veterinary case report
Malignant pheochromocytoma in a pig.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2012
- Authors:
- Martínez, Jorge et al.
- Affiliation:
- Departament de Sanitat i Anatomia Animals · Spain
Abstract
Endocrine tumors are rarely observed in pigs, and pheochromocytomas have been only punctually described. The current report describes a white and firm, 15-cm in diameter, neoplastic mass located in the adrenal gland with metastasis to regional lymph nodes in a 2.5-year-old sow. The masses had marked desmoplasia that supported a population of polygonal-to-spindle-shaped neoplastic cells arranged into cords and packets within a delicate fibrovascular stroma. Immunohistochemical staining of the tumor was positive for chromogranin and negative for neurofilament protein in adrenal and lymph node masses, which was characteristic of a malignant pheochromocytoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22362956/