Peer-reviewed veterinary case report
Dog with eye tumor spreading to brain and kidney
By Aleksandersen, Mona et al.·Published in Veterinary ophthalmology·2004·Department of Basic Sciences and Aquatic Medicine·View original on PubMed →
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Original publication title: Malignant teratoid medulloepithelioma with brain and kidney involvement in a dog.
- Species:
- dog
Plain-English summary
A 4-year-old Neapolitan mastiff was brought in with severe eye problems, including acute glaucoma in the left eye, which made it difficult to see deeper structures. Unfortunately, the dog also showed signs of neurological issues, leading to the decision to euthanize. A postmortem examination revealed a malignant tumor in the eye that had spread to the brain and one kidney. This type of tumor is rare and aggressive, and the findings highlight the serious nature of such conditions in dogs.
People also search for: dog eye tumor symptoms · Neapolitan mastiff brain cancer · acute glaucoma treatment in dogs
Abstract
ANIMAL STUDIED: A tumor of the left eye with involvement of the brain and kidney was diagnosed in a 4-year-old Neapolitan mastiff. PROCEDURE: The dog presented with acute glaucoma of the left eye. Peripheral corneal vascularization and severe corneal edema obscured examination of deeper structures. Because of concurrent progressive neurologic signs the dog was euthanized and a postmortem examination was performed. The eyes, brain and samples from the lung, heart, liver and kidneys were fixed in 4% neutral buffered formalin and embedded in paraffin wax. Sections were examined by light microscopy including histochemical and immunohistochemical staining. RESULTS: The ocular tumor originated from the ciliary body and was composed of small islets and cords of poorly differentiated, oval to polyhedral cells surrounded by abundant ground substance. Areas with chondroid differentiation were observed. Rosettes were not found. Metastases with the same morphology were present in the brain and in one kidney. CONCLUSION: An intraocular malignant teratoid medulloepithelioma with metastases to the brain and kidney is presented.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15511282/