Peer-reviewed veterinary case report
Malignant eye nerve tumor in 12-week-old silver Labrador Retriever
By Duke, F D et al.·Published in Veterinary pathology·2015·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Malignant uveal schwannoma with peripheral nerve extension in a 12-week-old color-dilute Labrador Retriever.
- Species:
- dog
Plain-English summary
A 12-week-old female silver Labrador Retriever was brought in with a collapsed front part of her eye and unusual growths on the iris. After testing, the vet found that she had a malignant schwannoma, a type of tumor affecting the eye's nerve tissue. Fortunately, six weeks after treatment, she showed no signs of new masses developing. This suggests that while the condition was serious, the immediate outcome was stable, and the dog did not experience further complications.
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Abstract
The formalin-fixed, amber-colored right globe from a 12-week-old female silver Labrador Retriever dog was submitted to the Comparative Ocular Pathology Laboratory of Wisconsin for light microscopic evaluation. The clinical history described a collapsed anterior chamber and multifocal nodular lesions in the peripheral iris. Histologically, immunohistochemically, and ultrastructurally, the uveal mass was consistent with a malignant schwannoma; there was extension along peripheral nerves within the sclera. The signalment and behavior of the neoplasm distinguish it from the uveal schwannoma of blue-eyed dogs and bear some resemblance to the ocular lesions in human neurofibromatosis. The dilute color mutation may contribute to the cause. Six weeks later, the dog did not develop any additional masses.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24513800/