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Peer-reviewed veterinary case report

Managing a mouse mutant resource center...this is not your father's transgenic core.

Journal:
Lab animal
Year:
2003
Authors:
Garrett-Beal, Lisa J & Hoogstraten, Shelley L
Affiliation:
National Human Genome Research Institute/NIH · United States
Species:
rodent

Plain-English summary

This study talks about how genetically engineered mice are becoming very important for medical research, leading many places to create special facilities just for these types of animals. The authors explain how the transgenic core at the National Human Genome Research Institute (NHGRI) is organized, how it works, and how it is managed. This information could help other institutions set up similar resources for their research needs.

Abstract

Genetically engineered mice are making an increasingly valuable contribution to biomedical research, and many institutions have begun to assemble dedicated facilities for the development of transgenic animals. The authors describe the structure, function, and management of the transgenic core at NHGRI.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/12966446/