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Peer-reviewed veterinary case report

Genetically engineered mice in biomedical research - what you need to

By Garrett-Beal, Lisa J & Hoogstraten, Shelley L·Published in Lab animal·2003·National Human Genome Research Institute/NIH, United States·View original on PubMed

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Original publication title: Managing a mouse mutant resource center...this is not your father's transgenic core.

Species:
rodent

Plain-English summary

This study talks about how genetically engineered mice are becoming very important for medical research, leading many places to create special facilities just for these types of animals. The authors explain how the transgenic core at the National Human Genome Research Institute (NHGRI) is organized, how it works, and how it is managed. This information could help other institutions set up similar resources for their research needs.

Abstract

Genetically engineered mice are making an increasingly valuable contribution to biomedical research, and many institutions have begun to assemble dedicated facilities for the development of transgenic animals. The authors describe the structure, function, and management of the transgenic core at NHGRI.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12966446/