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Peer-reviewed veterinary case report

Marburg Virus Aerosol Infection in Animal Models.

Journal:
Methods in molecular biology (Clifton, N.J.)
Year:
2025
Authors:
Bushmaker, Trenton
Affiliation:
National Institute for Allergy and Infectious Diseases · United States

Abstract

Aerosol challenge provides the ability to investigate in-depth mucosal virus exposure, including modeling of airborne transmission from high-consequence viral infection. For filoviruses, in particular Marburg and Ebola viruses, aerosol infection is considered in connection to their potential misuse. Aerosol exposure with filoviruses has been used to study disease progression, pathogenicity, and the efficacy of medical countermeasures. The aim of this protocol is to provide a general outline for aerosol exposure of animals with filoviruses, specifically Marburg virus.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/39585630/