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Peer-reviewed veterinary case report

Marginal siderosis and degenerative myelopathy: a manifestation of chronic subarachnoid hemorrhage in a horse with a myxopapillary ependymoma.

Journal:
Veterinary pathology
Year:
2000
Authors:
Huxtable, C R et al.
Affiliation:
Department of Biomedical Science · United States
Species:
horse

Plain-English summary

A 19-year-old Dutch Warm Blood horse was diagnosed with a condition called marginal siderosis, which involves damage to the brain and spinal cord due to bleeding in the area around them. This bleeding was linked to a type of tumor called a myxopapillary ependymoma. The horse showed signs of myelopathy, which means it had issues with its nervous system affecting movement and coordination. This case is notable because there has only been one other similar report in veterinary medicine. The outcome of the treatment for this horse is not mentioned in the abstract.

Abstract

Marginal siderosis is recognized in humans as an uncommon clinicopathologic entity characterized by degeneration of neural tissue at the surface of the brain and spinal cord, in association with the accumulation of hemosiderin, and resulting from chronic subarachnoid hemorrhage. The sources of hemorrhage are various and include neoplasms, malformations, cysts, and vasculopathy. Marginal siderosis of the spinal cord due to a myxopapillary ependymoma was diagnosed in a 19-year-old Dutch Warm Blood horse with clinical signs of myelopathy. There is only one previous report of marginal siderosis in the veterinary literature, also in a horse with clinical myelopathy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/11055876/