Peer-reviewed veterinary case report
Mass spectrometry in animal health laboratories: recent history, current applications, and future directions.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2024
- Authors:
- Filigenzi, Michael S
- Affiliation:
- University of California-Davis · United States
Plain-English summary
Mass spectrometry (MS) is a powerful tool used in laboratories to analyze substances, but its use in animal health has been limited due to high costs. Since around 2020, however, more animal health laboratories have started using MS techniques, which have proven helpful in areas like testing for toxins and identifying bacteria. Researchers are finding new ways to use MS, and it is expected to be beneficial in other fields such as studying viruses and diseases. Overall, the advancements in MS are opening up exciting possibilities for improving animal health diagnostics and treatments.
Abstract
Mass spectrometry (MS) has long been considered a cornerstone technique in analytical chemistry. However, the use of MS in animal health laboratories (AHLs) has been limited, however, largely because of the expense involved in purchasing and maintaining these systems. Nevertheless, since ~2020, the use of MS techniques has increased significantly in AHLs. As expected, developments in new instrumentation have shown significant benefits in veterinary analytical toxicology as well as bacteriology. Creative researchers continue to push the boundaries of MS analysis, and MS now promises to impact disciplines other than toxicology and bacteriology. I include a short discussion of MS instrumentation, more detailed discussions of the MS techniques introduced since ~2020, and a variety of new techniques that promise to bring the benefits of MS to disciplines such as virology and pathology.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39175303/