Peer-reviewed veterinary case report
Dog with large liver cancer treated by radiation therapy
By Toyloy, M et al.·Published in Schweizer Archiv fur Tierheilkunde·2021·Abteilung Radio-Onkologie·View original on PubMed →
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Original publication title: [Massive unresectable hepatocellular carcinoma in a dog treated with -intensity-modulated radiation therapy].
- Species:
- dog
Plain-English summary
A 12-year-old female mixed-breed dog was diagnosed with a large, inoperable liver tumor called hepatocellular carcinoma. After confirming the diagnosis with imaging and biopsies, the veterinarian decided against surgery due to the tumor's size and location near major blood vessels. Instead, the dog received radiation therapy, which successfully reduced the tumor size significantly. At follow-up visits three months and one year later, the dog was doing well, with normal liver function tests and a decrease in tumor size by up to 90%. Two years after treatment, the dog remained healthy with normal liver enzymes.
People also search for: dog liver cancer treatment · mixed-breed dog radiation therapy · hepatocellular carcinoma in dogs
Abstract
This case report describes a 12-year-old female spayed mixed-breed dog referred for treatment of a large, inoperable hepatocellular carcinoma. A computed tomography (CT) scan confirmed the previous ultrasonographic and laparoscopic findings of a large, lobulated, poorly defined mass on the left and central aspect of the liver. Multiple biopsies confirmed the diagnosis of hepatocellular carcinoma. Due to the large extent of the tumor, the vascular association to the Vena cava caudalis and the associated high risk of intraoperative bleeding, a resection of the mass was refrained from and a radiotherapeutic treatment was chosen. The dog underwent radiation therapy (RT) with a 6MV linear accelerator with 5×6 Gy, total dose 30 Gy. In the follow up examinations three months and one year after therapy, the dog presented in normal condition and had normal Alanine-amino-transferase (ALT) and alkaline phosphatase (AP). The tumor size measured in the CT-examinations decreased by 61% and 90%, respectively. Two years after radiation therapy the dog has a normal general condition and liver enzymes are within the normal limits.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34193402/