Peer-reviewed veterinary case report
Dog with spleen tumor made of mast and plasma cells
By Pallatto, Valarie A & Bechtold, Molly A·Published in Veterinary clinical pathology·2018·ANTECH Diagnostics, United States·View original on PubMed →
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Original publication title: Mast cell and plasma cell collision tumor in the spleen of a dog.
- Species:
- dog
Plain-English summary
A 9-year-old spayed female English Mastiff was brought to the vet after losing weight, vomiting, and not wanting to eat for three weeks. An ultrasound revealed several masses in her spleen, and tests showed an abnormal increase in certain proteins in her blood. A closer examination of the masses found that she had a rare type of tumor made up of both mast cells and plasma cells. This condition can be serious, so it's important for pet owners to discuss treatment options with their veterinarian.
People also search for: dog weight loss vomiting · English Mastiff spleen tumor · mast cell tumor treatment in dogs
Abstract
A 9-year-old spayed female English Mastiff was referred for outpatient ultrasound due to a 3-week history of weight loss, vomiting, and decreased appetite. Abdominal ultrasound showed multiple splenic masses of varying sizes and serum chemistry panel showed hyperglobulinemia. Cytologic examination of fine-needle aspirates of the splenic masses indicated a mast cell and plasma cell collision tumor. Results of serum and urine protein electrophoresis and immunofixation indicated the plasma cell neoplasia was producing IgA immunoglobulins.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29902336/