Peer-reviewed veterinary case report
Beagle dog with placenta-like uterine swelling and high progesterone
By Koguchi, A et al.·Published in Experimental animals·1995·Safety Research Laboratory, Japan·View original on PubMed →
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Original publication title: Maternal placenta-like endometrial hyperplasia in a beagle dog (Canine deciduoma).
- Species:
- dog
Plain-English summary
A 15-month-old female beagle was found to have unusual swellings in her uterus, even though she was not pregnant. Upon examination, the vet discovered that her uterus had grown abnormally, resembling a placenta but without a fetus. The dog's hormone levels showed high progesterone, which may have contributed to this condition. Unfortunately, the outcome was not positive, as the dog did not survive.
People also search for: beagle dog uterus problems · high progesterone in dogs · dog endometrial hyperplasia symptoms
Abstract
Three thumb-sized segmental swellings were found in both uterine horns of a 15 month-old, non-pregnant and non-pseudopregnant female beagle dog. Histopathological examination of the uterus revealed a marked proliferation of the endometrium that was characterized by two distinct parts, an inner tightly-folded banded layer and an outer dilated spongy layer, quite similar to the maternal placenta except for the fetus and chorion in the lumen. Because the plasma level of progesterone was unusually high at autopsy, this hormonal disorder might be related to the pathogenesis of the endometrial hyperplasia in the present case.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7556428/