Peer-reviewed veterinary case report
High manganese in brain linked to MRI changes in Yorkshire Terrier
By Torisu, Shidow et al.·Published in The Journal of veterinary medical science·2008·Nippon Veterinary and Life Science University, Japan·View original on PubMed →
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Original publication title: Measurement of brain trace elements in a dog with a portosystemic shunt: relation between hyperintensity on T1-weighted magnetic resonance images in lentiform nuclei and brain trace elements.
- Species:
- dog
Plain-English summary
A 5-year-old male Yorkshire Terrier was brought in for evaluation after surgery to treat a portosystemic shunt (a condition where blood bypasses the liver). Before euthanasia, an MRI showed unusual brightness in a part of the dog's brain called the lentiform nuclei. Tests revealed that manganese levels in this area were significantly higher than normal, suggesting that this buildup may have contributed to the MRI findings. Unfortunately, the dog's condition was severe, and the outcome was not positive.
People also search for: dog portosystemic shunt symptoms · Yorkshire Terrier brain MRI results · high manganese levels in dogs
Abstract
Prior to euthanasia, brain magnetic resonance imaging (MRI) was performed for a five-year-old male Yorkshire Terrier following portosystemic shunt (PSS) surgical attenuation. Hyperintensity was observed on T1W images of the lentiform nuclei. Trace elements in this area were measured by inductively coupled plasma atomic emission spectrometry. The manganese concentration in the lentiform nuclei was four times higher than that in the control group. Therefore, the manganese accumulation would be the substance that causes the hyperintensity on T1W images of the lentiform nuclei in PSS dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19122413/