Peer-reviewed veterinary case report
Measuring cat lipase with dry-chemistry test versus Spec fPL
By Oishi, Mariko et al.·Published in The Journal of veterinary medical science·2015·Veterinary Medical Center and Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Measurement of feline lipase activity using a dry-chemistry assay with a triolein substrate and comparison with pancreas-specific lipase (Spec fPL(TM)).
- Species:
- cat
Plain-English summary
A study found that a new blood test for measuring lipase activity in cats may help screen for pancreatitis, a painful inflammation of the pancreas. While the test showed high accuracy in ruling out the disease, it didn't correlate well with the more established test, Spec fPL, in diagnosing pancreatitis. This means that while the new test could be useful for checking if a cat likely does not have pancreatitis, it may not be reliable for confirming the disease. Pet owners should consult their veterinarian about the best testing options if their cat shows symptoms like vomiting or loss of appetite.
People also search for: cat pancreatitis symptoms · feline lipase test · how to diagnose cat pancreatitis
Abstract
Pancreatic lipase immunoreactivity (Spec fPL) is currently considered to be the most accurate blood test for the diagnosis of feline pancreatitis. In this study, we measured lipase activity in cats using a newer catalytic lipase assay of dry-chemistry system (FDC-v-LIP) to determine the reference range and compared the results with those for Spec fPL. Based on the results of healthy cats, the reference range of FDC-v-LIP was determined to be less than 30 U/l. FDC-v-lip did not show a strong correlation with Spec fPL in cats with various diseases, which resulted in the low sensitivity and positive predictive value. However, the relatively high (>90%) specificity and negative predictive value indicated that FDC-v-LIP could be a useful patient-side screening test for the exclusion of feline pancreatitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26050751/