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Peer-reviewed veterinary case report

Vitamin E levels in joint fluid of dogs with cruciate ligament

By de Oliveira El-Warrak, Alexander et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2012·D&#xe9·View original on PubMed

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Original publication title: Measurement of vitamin A, vitamin E, selenium, and L-lactate in dogs with and without osteoarthritis secondary to ruptured cranial cruciate ligament.

Species:
dog

Plain-English summary

A group of dogs with osteoarthritis (OA) caused by a torn cranial cruciate ligament was compared to healthy dogs to check their vitamin levels. The study found that dogs with OA had higher levels of vitamin E in their joint fluid than those without OA. However, other vitamins and minerals like selenium and vitamin A did not show significant differences between the two groups. This research suggests that vitamin E may play a role in joint health for dogs with OA.

People also search for: dog osteoarthritis treatment · vitamin E for dogs with joint pain · torn cruciate ligament in dogs

Abstract

This study compared vitamin A, vitamin E, selenium (Se), and L-lactate in blood and synovial fluid in 2 groups of 6 dogs; a control group (without OA) and an osteoarthritic group with spontaneous cranial cruciate ligament rupture and OA. Concentrations of vitamin E were significantly higher in serum than in synovial fluid in both OA (P = 0.006) and control (P = 0.0008) groups. Vitamin E concentration in synovial fluid was significantly higher in the OA group than in the control group (P = 0.009). Concentrations of Se were significantly higher in serum than in synovial fluid in both OA (P = 0.003) and control (P = 0.0006) groups. There were no significant differences in levels of Se, vitamin A, and L-lactate between the 2 groups. This is the first study to show an increased concentration of vitamin E in the synovial fluid of dogs with OA compared with dogs that did not have OA.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23729826/