Peer-reviewed veterinary case report
Measuring impulsivity in mice: the five-choice serial reaction time task.
- Journal:
- Psychopharmacology
- Year:
- 2012
- Authors:
- Sanchez-Roige, Sandra et al.
- Affiliation:
- School of Psychology · United Kingdom
- Species:
- rodent
Abstract
RATIONALE: Mice are useful tools for dissecting genetic and environmental factors in relation to the study of attention and impulsivity. The five-choice serial reaction time task (5CSRTT) paradigm has been well established in rats, but its transferability to mice is less well documented. OBJECTIVES: This study aims to summarise the main results of the 5CSRTT in mice, with special focus on impulsivity. METHODS: The 5CSRTT can be used to explore aspects of both attentional and inhibitory control mechanisms. RESULTS: Different manipulations of the task parameters can lead to different results; adjusting the protocol as a function of the main variable of interest or the standardisation of the protocol to be applied to a large set of strains will be desirable. CONCLUSIONS: The 5CSRTT has proven to be a useful tool to investigate impulsivity in mice.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22089700/