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Peer-reviewed veterinary case report

Medical management and positive outcome after prolonged recumbency in a case of equine herpesvirus myeloencephalopathy.

Journal:
Journal of equine veterinary science
Year:
2024
Authors:
Mannini, A et al.
Affiliation:
Department of Veterinary Medical Sciences (DIMEVET) · Italy
Species:
horse

Plain-English summary

A 17-year-old mare developed a high fever, weakness, and trouble with her bladder, leading to a diagnosis of equine herpesvirus myeloencephalopathy (EHM). She became unable to stand for a time and required various treatments, including fluids, plasma, anti-inflammatory medications, and a catheter for her bladder. After being hospitalized for 10 days, she showed some neurological issues, particularly with her hind legs, and developed additional problems like a bladder infection and corneal ulcers. With continued medical care and support, her condition gradually improved over 34 days, and she was eventually sent home with some lingering weakness. At an eight-month follow-up, she had made significant progress in her ability to move around.

Abstract

A 17-year-old mare presenting with acute fever, weakness and bladder dysfunction was diagnosed with equine herpesvirus myeloencephalopathy (EHM). The mare become transiently recumbent, underwent parenteral fluid therapy, plasma infusion, steroidal/nonsteroidal anti-inflammatory drugs (SAID/NSAIDs) and bladder catheterization. After 10 days the mare was hospitalized. Neurological evaluation revealed ataxia and proprioceptive deficits mainly in the hind limbs. The mare was able to stand but unable to rise from recumbency or walk. Secondary complications included Escherichia coli cystitis, corneal ulcers and pressure sores. A full-body support sling was used for 21 days. Medical treatment included systemic antimicrobials, NSAIDs, gradual discontinuation of SAIDs, parenteral fluid therapy and bladder lavage. The mare tested positive for Varicellovirus equidalpha 1 (EHV-1) DNA in nasal swab and blood samples on day 13 and in urine samples on days 13 and 25 after the onset of fever. Neurological signs improved over a period of 34 days and the mare was discharged with mild hind limb weakness/ataxia. Secondary complications resolved within 2 weeks. At the eight-month follow-up, marked improvement in locomotory function had been achieved.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38608970/