Peer-reviewed veterinary case report
Brain tumor surgery and chemo in 6-year-old dog
By R. Lampe et al.·Published in Frontiers in Veterinary Science·2019·View original on Semantic Scholar →
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Original publication title: Medulloblastoma in a 6 Year Old Mixed Breed Dog: Surgical Debulking and Chemotherapy
- Species:
- dog
Plain-English summary
A 6-year-old American Staffordshire Terrier was diagnosed with a brain tumor called medulloblastoma and underwent surgery to remove as much of it as possible. After surgery, the dog received a combination of chemotherapy drugs, which helped improve her condition significantly for a while. Unfortunately, after five months, her health declined, leading to euthanasia. This case highlights the importance of considering treatment options from human medicine for rare brain tumors in dogs, suggesting that surgery and chemotherapy can be effective for similar cases.
People also search for: dog brain tumor treatment · American Staffordshire Terrier medulloblastoma · chemotherapy for dog brain cancer
Abstract
A medulloblastoma was surgically debulked from a 6 year old American Staffordshire Terrier, who then received a modified lomustine (CCNU), vincristine, procarbazine, and prednisolone (LOPP) protocol. The dog improved significantly and continued to do well until deterioration and euthanasia 5 months following surgery. This is the first known published case report of surgical cytoreductive surgery of a medulloblastoma in a dog with documented response to surgery and chemotherapy. Medulloblastoma is a primitive neuroectodermal tumor that is the most common malignant central nervous system (CNS) tumor in children, though it is less common in adults. This case illustrates the value of considering human literature when creating treatment plans for uncommon brain tumors in veterinary patients. Medulloblastoma should be a differential for cerebellar tumors in young to middle aged dogs, and surgery and chemotherapy should be considered.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/31799282