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Peer-reviewed veterinary case report

Melamine and cyanuric acid-induced crystalluria, uroliths, and nephrotoxicity in dogs and cats.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2009
Authors:
Osborne, Carl A et al.
Affiliation:
Veterinary Clinical Sciences Department · United States

Plain-English summary

In 2007, there was a recall of canned pet food due to worries about how it could harm the kidneys of dogs and cats. The food was found to contain harmful substances called melamine and cyanuric acid. The article shares case studies that look at the health issues these pets faced, including tests and findings related to their kidneys and urinary stones. Researchers are also trying to figure out the minerals present in the stones and kidney tissues of the animals that were affected. Overall, the article highlights serious health risks linked to these toxic substances in pet food.

Abstract

This article discusses the 2007 recall of canned pet food because of concerns about adverse effects on kidney function of cats and dogs. The discovery of melamine and cyanuric acid in the foods is detailed. Case studies, including clinical, pathology, histology, and toxicology findings, are presented. An attempt is being made to identify the minerals in the uroliths and kidney tissues of affected animals.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/19038647/