Peer-reviewed veterinary case report
Kidney tumor found in young female Entlebucher Mountain Dog
By Lockow, Sandra et al.·Published in Journal of comparative pathology·2026·Department of Pathology, Germany·View original on PubMed →
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Original publication title: Mesoblastic nephroma in a young Entlebucher Mountain Dog.
- Species:
- dog
Plain-English summary
A 16-month-old female Entlebucher Mountain Dog was brought to the vet in poor health, showing signs of gastrointestinal issues. An ultrasound revealed a mass in her right kidney, leading to surgery where the kidney and ovaries were removed. The tumor was identified as a congenital mesoblastic nephroma, a type of kidney tumor. After three years of follow-up, the dog was doing well and showed no signs of illness, indicating that the surgery was successful.
People also search for: dog kidney tumor treatment · Entlebucher Mountain Dog health issues · gastrointestinal problems in dogs
Abstract
An intact 16-month-old female Entlebucher Mountain Dog in poor general condition was presented with clinical signs of gastrointestinal disease. Abdominal ultrasonography revealed a mass in the right kidney. Nephrectomy combined with ovariohysterectomy was performed. Histology revealed a mesenchymal tumour that was composed of neoplastic spindle cells forming interlacing fascicles, whorls and bundles, and embedded into a loose myxoid to dense collagenous stroma. Immunohistochemically, neoplastic cells diffusely labelled for vimentin and partially for S-100 protein and p75. Based on these results, the tumour was diagnosed as a classical variant of a congenital mesoblastic nephroma. The expression of p75has not been described in this tumour entity before and its significance with regard to tumour promoting or tumour suppressing function or indication of a neurogenic differentiation remains undetermined. After a 3-year follow-up the dog was clinically healthy, indicating a successful surgical treatment.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41265286/