Peer-reviewed veterinary case report
Dog with liver metastasis from thymoma tumor in chest
By Wiles, Valerie et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2018·Veterinary Cancer Group·View original on PubMed →
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Original publication title: Metastatic thymoma in the liver of a dog.
- Species:
- dog
Plain-English summary
A 12-year-old neutered male Portuguese Water dog was brought in due to a year-long struggle with poor appetite, diarrhea, and repeated urinary infections. Tests showed liver nodules and an enlarged spleen, along with a mass in the chest area. Further examination indicated that the dog had a thymoma, a type of tumor, that had spread to the liver. After confirming the diagnosis through tissue samples, the veterinarian could determine the best treatment plan for the dog.
People also search for: dog liver nodules · Portuguese Water dog thymoma treatment · dog diarrhea and poor appetite · recurrent urinary infection in dogs
Abstract
A 12-y-old neutered male Portuguese Water dog was presented because of a 1-y history of persistent hyporexia, diarrhea, and recurrent pyelonephritis. Abdominal ultrasound revealed hepatic nodules and diffuse splenomegaly, and radiographs revealed a mediastinal mass. Fine-needle aspirates of the liver, spleen, and mediastinal mass were suspicious for lymphoma. Flow cytometry identified small T cells that co-expressed CD4 and CD8 at all sites, most suspicious for thymoma, but lymphoma could not be ruled out. PCR for antigen receptor rearrangements analysis identified polyclonal amplification of the T-cell receptor genes, more consistent with thymoma than lymphoma. Histopathology of the liver and thymic mass confirmed thymoma with hepatic metastasis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30117785/