Peer-reviewed veterinary case report
Methocarbamol CRI for symptomatic treatment of pyrethroid intoxication: a report of three cases.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 2013
- Authors:
- Draper, William E et al.
- Affiliation:
- Department of Small Animal Clinical Sciences · United States
Plain-English summary
This report discusses three pets—two cats and one dog—that experienced poisoning from pyrethroids, which are chemicals often used to kill insects and are generally safe for pets but can cause problems if misused or accidentally ingested. The cats are particularly vulnerable to these toxins. The pets were treated with a steady infusion of methocarbamol, a medication commonly used to help with muscle tremors caused by this type of poisoning. Thankfully, all three pets showed improvement within a few hours without any negative side effects from the treatment. This suggests that using methocarbamol in a continuous infusion can be an effective option for treating pyrethroid poisoning in pets.
Abstract
Pyrethroids are popular for use in companion animals due to their relatively low mammalian toxicity and efficacy against arthropods. Nonetheless, pyrethroid intoxication has been reported in cats and dogs, and cats appear to be more susceptible due to difficulty in biotransformation and excretion of pyrethroids. Pyrethroid intoxications are generally due to either the improper use or accidental ingestion of approved products. Methocarbamol, given as intermittent injections, is a common first-line treatment choice for the tremors associated with pyrethroid intoxication. Two cats and one dog were treated with a methocarbamol continuous rate infusion (CRI) for pyrethroid intoxication. Clinical signs of toxicity resolved within a few hr in all three cases, with no adverse drug effects. A methocarbamol CRI can be considered in animals presenting with pyrethroid intoxication.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23535756/