Peer-reviewed veterinary case report
Dog and cat tremors from pyrethroid poisoning - treatment with
By Draper, William E et al.·Published in Journal of the American Animal Hospital Association·2013·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Methocarbamol CRI for symptomatic treatment of pyrethroid intoxication: a report of three cases.
Plain-English summary
A cat and a dog were brought in after showing signs of poisoning from pyrethroid products, which are often used for pest control but can be harmful if misused. Both pets were treated with a continuous infusion of methocarbamol, a medication that helps control muscle tremors caused by the poisoning. Fortunately, their symptoms improved within a few hours, and there were no negative side effects from the treatment. This case suggests that methocarbamol can be an effective option for pets suffering from pyrethroid intoxication.
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Abstract
Pyrethroids are popular for use in companion animals due to their relatively low mammalian toxicity and efficacy against arthropods. Nonetheless, pyrethroid intoxication has been reported in cats and dogs, and cats appear to be more susceptible due to difficulty in biotransformation and excretion of pyrethroids. Pyrethroid intoxications are generally due to either the improper use or accidental ingestion of approved products. Methocarbamol, given as intermittent injections, is a common first-line treatment choice for the tremors associated with pyrethroid intoxication. Two cats and one dog were treated with a methocarbamol continuous rate infusion (CRI) for pyrethroid intoxication. Clinical signs of toxicity resolved within a few hr in all three cases, with no adverse drug effects. A methocarbamol CRI can be considered in animals presenting with pyrethroid intoxication.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23535756/