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Peer-reviewed veterinary case report

Methylene blue-mediated antimicrobial photodynamic therapy for canine dermatophytosis caused by Microsporum canis: A successful case report with 6 months follow-up.

Journal:
Photodiagnosis and photodynamic therapy
Year:
2021
Authors:
Cabral, Fernanda V et al.
Affiliation:
Energy and Nuclear Research Institute (IPEN/CNEN) · Brazil
Species:
dog

Plain-English summary

A 7-year-old male dog was diagnosed with a skin infection caused by a fungus called Microsporum canis, which is common in pets and can spread to people. To treat this infection, the dog received a special light therapy using a dye called methylene blue, applied to the affected areas in two sessions a week apart. After 21 days, the dog was completely healed, and there were no signs of the infection returning even after six months. This treatment shows promise for helping pets with similar skin infections and could be worth discussing with your veterinarian.

Abstract

Dermatophytosis is a superficial skin infection that widely effects companion animals. Miscrosporum canis is one of the most prevalent species isolated from dogs and cats, and because of the serious zoonotic potential, short-term treatment regimens are preferred to prevent the spread of disease either by direct contact or through contamination of the environment. Antimicrobial photodynamic therapy (APDT) has emerged as a promising strategy able to kill effectively a wide range of pathogens in a short period with minimal morbidity . In this case report, a 7-year-old male dog was diagnosed with dermatophytosis caused by M. canis. Methylene blue-mediated antimicrobial photodynamic therapy (MB-APDT) was applied over the lesions in two sessions with an interval of 7 days. The dog successfully healed, achieving a complete clinical cure after 21 days, without reports of recurrence after a follow-up period of 6 months. Therefore, MB-APDT could be a potential ally of small animal clinicians to treat superficial fungal diseases and should be further explored in Veterinary Medicine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/34706277/