Peer-reviewed veterinary case report
Gut bacteria and feces changes in Yorkshire Terriers with chronic gut
By Galler, Alexandra I et al.Ā·Published in Scientific reportsĀ·2022Ā·University of Veterinary MedicineĀ·View original on PubMed ā
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research ā every detail traces back to the citation above. How we work ā
Original publication title: Microbial dysbiosis and fecal metabolomic perturbations in Yorkshire Terriers with chronic enteropathy.
- Species:
- dog
Plain-English summary
A group of Yorkshire Terriers with chronic enteropathy (a type of inflammatory bowel disease) showed signs of gut imbalance and changes in their stool composition. The study found that these dogs had higher levels of certain fatty acids and lower levels of beneficial bacteria compared to healthy dogs. Even after treatment, while some fatty acid levels improved, the overall gut health did not fully return to normal. This suggests that Yorkshire Terriers may have unique issues related to their gut health that could affect their recovery.
People also search for: Yorkshire Terrier chronic enteropathy treatment Ā· dog gut health issues Ā· inflammatory bowel disease in dogs
Abstract
Dysbiosis and perturbations of fecal metabolic profiles have been reported in dogs with inflammatory bowel disease. Currently the incidence of dysbiosis and the fecal metabolomic profile in Yorkshire Terriers with chronic enteropathy (YTE) and the effects of treatment are unknown. This prospective observational study analyzed the dysbiosis index (DI) and fecal bile acid, sterol and fatty acid profiles in 14 Yorkshire Terriers with active YTE, 11 dogs in clinical remission, and 26 healthy Yorkshire Terriers. YTE was associated with dysbiosis and a significant increase in fatty acids (docosanoate, p = 0.002; gondoate, p = 0.026; erucate, p < 0.001; nervonate, p < 0.001; linolenate, p < 0.001), and plant sterols (campesterol, p < 0.001; brassicasterol, p = 0.024). The abundances of Fusobacterium (p < 0.001) and Cl. hiranonis (p = 0.018) and the concentrations of the secondary bile acid ursodeoxycholic acid (p = 0.033) and the plant sterol sitostanol (p = 0.003) were significantly decreased compared to healthy dogs. Dysbiosis, abundances of Fusobacterium, Cl. hiranonis and fecal concentrations of bile acids and sterols did not recover after treatment, while fecal fatty acid concentrations decreased in treated dogs. YTE is associated with dysbiosis and changes in bile acid, fatty acid, and sterol metabolism. These changes only recovered partially despite clinical remission. They might be breed-specific and involved in the pathogenesis of YTE.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35902689/