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Peer-reviewed veterinary case report

Microgravity Exacerbates Periodontitis In Vivo.

Journal:
Journal of periodontal research
Year:
2025
Authors:
Bakri, Ahmed et al.
Affiliation:
College of Dental Medicine

Abstract

This is the first study to examine induced periodontitis under simulated microgravity in vivo. Microgravity significantly increased alveolar bone loss, elevated GCF alkaline phosphatase levels, and caused severe periodontal destruction with notable immune cell infiltration. Understanding the underlying molecular pathways may guide future treatments for periodontitis in space and on Earth.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40448419/