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Peer-reviewed veterinary case report

MicroRNAs in equine veterinary science.

Journal:
Equine veterinary journal
Year:
2018
Authors:
Hollis, A R & Starkey, M P
Affiliation:
Animal Health Trust · United Kingdom
Species:
horse

Abstract

MicroRNAs are small noncoding RNAs that play a pivotal role in diverse cellular processes through post-transcriptional regulation of gene expression. The dysregulation of specific microRNAs is associated with disease development and progression. In this review, we summarise how microRNAs modulate gene expression, and explain microRNA nomenclature. We discuss the potential applications of microRNAs in equine disease diagnosis and treatment, in the context of the sum of current knowledge about microRNA expression in normal and diseased equine tissues.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29672919/