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Peer-reviewed veterinary case report

Mid-infrared reflectivity of experimental atheromas.

Journal:
Journal of biomedical optics
Year:
2008
Authors:
Holman, Hoi-Ying N et al.
Affiliation:
University of California · United States
Species:
rodent

Abstract

We report that the pathologic components present within the atheromatous plaques of ApoE knock-out mice can reflect significant amounts of mid-infrared (mid-IR) light. Furthermore, the reflected light spectra contained the unique signatures of a variety of biologic features including those found in unstable or "vulnerable" plaque. This discovery may represent a unique opportunity to develop a new intravascular diagnostic modality that can detect and characterize sites of atherosclerosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18601520/