Mimicking Alveolar Lung Structures with Lattice Designs.

Abstract

Advances in additive manufacturing (AM) have revolutionized various sectors, including aerospace engineering, where the use of lattice structures has enabled the development of lightweight high-performance components with optimized mechanical properties. Building on these engineering principles, this study explores the application of aerospace-derived lattice design strategies to the biomedical field, specifically for the replication of human lung alveolar structures. The objective is to create anatomically accurate 3D-printed lung models suitable for surgical planning. Finite element analyses have been conducted using a CAD model of adult lungs, including the application of lattice structures generated through nTopology software, to evaluate the elasticity and density, critical for simulating lung mechanics. A preliminary prototype has been produced using stereolithography and flexible resin, showing the potential for realistic tactile feedback.