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Peer-reviewed veterinary case report

Minimizing strain influences in a genetically modified mouse phenotyping platform.

Journal:
Annals of the New York Academy of Sciences
Year:
2011
Authors:
Hayward, Michael D et al.
Affiliation:
Taconic · United States

Abstract

Our approach has been to power studies to allow for detection of at least modest changes from a wild-type littermate control, include assays with overlapping physiological systems to provide cross-functional interpretive value, and to employ challenge assays.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22211971/