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Peer-reviewed veterinary case report

Cat with hyperadrenocorticism treated successfully with mitotane

By Schwedes, C S·Published in The Journal of small animal practice·1997·Tier&#xe4, Germany·View original on PubMed

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Original publication title: Mitotane (o,p'-DDD) treatment in a cat with hyperadrenocorticism.

Species:
cat

Plain-English summary

An 11-year-old male Persian cat was brought to the vet for treatment of hyperadrenocorticism, a condition that causes the adrenal glands to produce too much cortisol. The cat's adrenal glands were found to be enlarged and calcified. After starting long-term treatment with mitotane, the signs of hyperadrenocorticism improved, and the cat's diabetes also resolved after about 220 days of therapy. The treatment was well-tolerated, with no serious side effects reported.

People also search for: cat hyperadrenocorticism treatment · Persian cat diabetes · mitotane for cats

Abstract

An 11-year-old male castrated Persian cat with spontaneous hyperadrenocorticism was presented. Both adrenals were grossly enlarged and calcified. A diagnosis of pituitary-dependent hyperadrenocorticism was made. Signs of hyperadrenocorticism resolved with long-term mitotane treatment. Concurrent diabetes mellitus resolved after 220 days of therapy. No severe adverse drug reactions were noted.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9403812/