Peer-reviewed veterinary case report
Heart function measures MAPSE and TAPSE are lower in cats
By Spalla, I et al.·Published in Journal of veterinary internal medicine·2017·Royal Veterinary College, United Kingdom·View original on PubMed →
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Original publication title: Mitral Annular Plane Systolic Excursion and Tricuspid Annular Plane Systolic Excursion in Cats with Hypertrophic Cardiomyopathy.
- Species:
- cat
Plain-English summary
A group of 64 cats with hypertrophic cardiomyopathy (HCM), a heart condition that can lead to serious problems, were studied to see how their heart function compared to healthy cats. The researchers found that cats with HCM had lower measurements of heart function, especially those showing signs of congestive heart failure (CHF), which is when the heart can't pump blood effectively. Cats with lower heart function measurements had a shorter survival time. This suggests that monitoring these heart function measures could help veterinarians predict outcomes for cats with HCM and CHF.
People also search for: cat heart disease symptoms · hypertrophic cardiomyopathy in cats · congestive heart failure in cats treatment
Abstract
BACKGROUND: Left ventricular (LV) systolic dysfunction is associated with increased risk of death in cats with hypertrophic cardiomyopathy (HCM). Mitral and tricuspid annular plane systolic excursion (MAPSE and TAPSE, respectively) are measures of longitudinal systolic function and are reduced in human patients with HCM. HYPOTHESES: Cats with HCM have lower MAPSE and TAPSE compared to control cats; lower MAPSE and TAPSE are associated with the presence of congestive heart failure (CHF) and reduced survival time. ANIMALS: 64 cats with HCM and 27 healthy cats. Forty-five cats with HCM were not showing clinical signs, and 19 had CHF. METHODS: Retrospective study. Anatomic M-mode from the left apical 4-chamber view was used to record MAPSE from the free wall (MAPSE FW) and septum (MAPSE IVS) and TAPSE. RESULTS: Compared to controls, cats with HCM had lower MAPSE IVS (controls 5.2 [4.6-5.6] mm, asymptomatic HCM 4.7 [4.1-5.2] mm, HCM with CHF 2.6 [2.5-3.2] mm, P < .001), MAPSE FW (controls 5.9 [5.3-6.2] mm, asymptomatic HCM 4.7 [4.1-5.1] mm, HCM with CHF 2.8 [2.4-3.2] mm) and TAPSE (controls 8.6 [7.4-10.2] mm, asymptomatic HCM 7.2 [6.3-8.2] mm, HCM with CHF 4.6 [4.1-5.4] mm), with the lowest in the CHF group. Univariate survival analysis showed a shorter survival in cats displaying lower MAPSE IVS, MAPSE FW, and TAPSE. CONCLUSIONS AND CLINICAL IMPORTANCE: MAPSE and TAPSE were lower in cats with HCM than in control cats and were lowest in CHF, suggesting that systolic longitudinal dysfunction is present in cats with HCM. MAPSE and TAPSE have potential prognostic significance.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28370313/