Peer-reviewed veterinary case report
Dog with rare heart lining cancer showing bone tissue growth
By Yamamoto, S et al.·Published in Journal of comparative pathology·2013·Tokyo University of Agriculture and Technology, Japan·View original on PubMed →
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Original publication title: Mixed form of pericardial mesothelioma with osseous differentiation in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old female Yorkshire terrier was brought in for treatment of recurring fluid buildup around her heart, known as pericardial effusion. Despite attempts to drain the fluid and a surgical procedure to remove part of the pericardium, the dog sadly passed away during surgery. A post-mortem examination revealed a rare type of tumor called pericardial mesothelioma, which had both soft and bony tissue components. This case is significant as it appears to be the first documented instance of this specific tumor in a dog.
People also search for: dog heart fluid buildup · Yorkshire terrier pericardial effusion · dog heart tumor treatment
Abstract
An 8-year-old female Yorkshire terrier was referred for evaluation and treatment of recurrent pericardial effusion. Echocardiographic examination revealed a markedly and irregularly thickened pericardial sac with frequent hyperechoic areas with acoustic shadows. Pericardiocentesis produced only a small amount of thick serosanguineous fluid. The dog underwent subtotal pericardiectomy, but died during surgery. At necropsy examination, the heart was encased by voluminous, grey-white to red-tan, soft to firm proliferative tissue arising from the pericardial sac. The pericardial cavity was obliterated. Microscopically, the tissue was predominantly sarcomatoid with osseous differentiation and epithelioid elements were admixed with bundles of spindle cells. Immunohistochemically, the constituent cells, especially those that were epithelioid, co-expressed cytokeratin and vimentin. A diagnosis of mixed form pericardial mesothelioma with osseous differentiation was made. This appears to be the first report of such a tumour in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23578582/