Peer-reviewed veterinary case report
Model for generation of large numbers of primary, inflammatory skin-derived neutrophils, and macrophages.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2013
- Authors:
- John, Dominik et al.
- Affiliation:
- Department of Dermatology · Germany
Abstract
Tissue macrophages and inflammatory neutrophils represent important cells of the innate immune system responsible for various important tasks, i.e., elimination of pathogens and/or granuloma formation. Isolation of large numbers of primary phagocytes is vital for research with these cells. Within this protocol, we present a strategy for isolation of large numbers of inflammatory neutrophils and macrophages from murine skin that allows for follow-up in vivo or in vitro studies.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23325660/