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Peer-reviewed veterinary case report

Model of Osteomyelitis in Rats.

Journal:
Bulletin of experimental biology and medicine
Year:
2022
Authors:
Ovchinnikov, E N et al.
Affiliation:
G. A. Ilizarov National Medical Research Centre for Traumatology and Orthopedics
Species:
rodent

Abstract

We developed a rat model of chronic osteomyelitis of the femur caused by Staphylococcus aureus. The clinical, histomorphological, and laboratory signs were compared in rats with osteomyelitis (infected) and control animals receiving saline. On day 21 after infection, clinical, histomorphological, and laboratory signs of chronic osteomyelitis were found in experimental rats.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35852691/