Peer-reviewed veterinary case report
Modulation of horizontally acquired genes by the Hha-YdgT proteins in Salmonella enterica serovar Typhimurium.
- Journal:
- Journal of bacteriology
- Year:
- 2008
- Authors:
- Vivero, Aitziber et al.
- Affiliation:
- Departament de Microbiologia · Spain
Abstract
We describe a transcriptomic study of the effect of hha and ydgT mutations in Salmonella enterica serovar Typhimurium. A large number of genes showing altered expression are located in AT-rich horizontally acquired DNA sequences. Many of these genes have also been reported to be targets for H-NS. As Hha and YdgT interact with H-NS, our findings strongly suggest that Hha and/or YdgT must form complexes with H-NS when they silence these DNA regions.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18039769/