Peer-reviewed veterinary case report
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity.
- Journal:
- Natural product reports
- Year:
- 2010
- Authors:
- Ostash, Bohdan & Walker, Suzanne
- Affiliation:
- Department of Microbiology and Molecular Genetics · United States
Abstract
The review (with 214 references cited) is devoted to moenomycins, the only known group of antibiotics that directly inhibit bacterial peptidoglycan glycosytransferases. Naturally occurring moenomycins and chemical and biological approaches to their derivatives are described. The biological properties of moenomycins and plausible mechanisms of bacterial resistance to them are also covered here, portraying a complete picture of the chemistry and biology of these fascinating natural products
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20730219/