Molasses, Antox® and EN-FLORAX® decreased antibody decay rate and enhanced response to a very virulent infectious bursal disease virus and Newcastle disease vaccine La Sota in ISA Brown chicks.

Abstract

This study evaluated the effects of molasses, Antox&#xae; and EN-FLORAX&#xae; on antibody (Ab) decay and response to a very virulent IBD virus (vvIBDV) and ND vaccine La Sota (NDVLS) in ISA Brown chicks. Five groups, (A, B, C, D and E) of 50 chicks each were used for the study. Groups A, B and C were supplemented with molasses, Antox&#xae; and EN-FLORAX&#xae;, respectively, orally from 1 to 49&#xa0;days, and inoculated with a vvIBDV at 28&#xa0;days of age. Groups D, and E were positive, and negative controls, respectively. At 35&#xa0;days of age, all groups were vaccinated with NDVLS. Antibody (Ab) titers to vvIBDV, and NDV, were determined by indirect enzyme linked immunosorbent assay (I-ELISA), and hemagglutination-inhibition (HI) tests, respectively. Results revealed significantly (P&#xa0;<&#xa0;.05) decreased Ab decay rates in supplemented groups (A, B, and C) compared to controls (D and E) up to day 28. There were significantly (P&#xa0;<&#xa0;.05) higher mean IBDV and ND HI Ab titers in supplemented groups compared to D with the highest in A up to day 49. Molasses, Antox&#xae;, and EN-FLORAX&#xae; decreased rate of Ab decay, elicited stronger Ab response against vvIBDV and production of protective NDVLS HI Ab titers.