Peer-reviewed veterinary case report
Dog with hepatitis linked to new canine minute virus strain
By Choi, Jeong-Won et al.·Published in Archives of virology·2016·Animal Disease Diagnostic Division, South Korea·View original on PubMed →
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Original publication title: Molecular characteristics of a novel strain of canine minute virus associated with hepatitis in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old female Yorkshire terrier died a few days after undergoing surgery for a hernia and spaying. A thorough examination revealed that the surgeries were not the cause of death; instead, she had degenerative viral hepatitis caused by a newly identified strain of the canine minute virus (MVC). This virus was found in her liver and other organs, and no other pathogens were detected. Unfortunately, the dog did not survive, but the findings suggest that this new strain of MVC could be linked to hepatitis in dogs.
People also search for: dog hepatitis symptoms · Yorkshire terrier viral infection · canine minute virus treatment
Abstract
A 5-year-old female Yorkshire terrier dog died a few days following hernia and ovariohysterectomy surgeries. Necropsy performed on the dog revealed that the surgeries were not the cause of death; however, degenerative viral hepatitis, showing intranuclear inclusion bodies in hepatic cells, was observed in histopathologic examination. Several diagnostic methods were used to screen for the cause of disease, and minute virus of canines (MVC) was detected in all parenchymal organs, including the liver. Other pathogens that may cause degenerative viral hepatitis were not found. Infection with MVC was confirmed by in situ hybridization, which revealed the presence of MVC nucleic acid in the liver tissue of the dog. Through sequencing and phylogenetic analysis of the nearly complete genome sequence, the strain was found to be distinct from other previously reported MVC strains. These results indicate that this novel MVC strain might be related to degenerative viral hepatitis in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27251050/