Peer-reviewed veterinary case report
Molecular characterization of a canine coronavirus NA/09 strain detected in a dog's organs.
- Journal:
- Archives of virology
- Year:
- 2012
- Authors:
- Ntafis, Vasileios et al.
- Affiliation:
- Department of Anatomy and Physiology of Farm Animals
- Species:
- dog
Abstract
In the present study, the detection of a pantropic canine coronavirus (CCoV) strain in a dog with lethal diarrhoea is reported. RT-PCR and real-time RT-PCR assays were used for the detection, characterization and quantitation of CCoV. Sequence and phylogenetic analysis of the CCoV NA/09 revealed a high degree of sequence identity with the pantropic strain CB/05, indicating the presence of CB/05-like pantropic strains in Greece. The absence of the 38-nucleotide deletion in ORF3b, which is characteristic of CB/05, indicates the need to identify new genetic markers for pantropic variants of CCoV, probably in the spike-protein gene region.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22002680/