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Peer-reviewed veterinary case report

Canine coronavirus strain NA/09 found in dog organs with deadly

By Ntafis, Vasileios et al.·Published in Archives of virology·2012·Department of Anatomy and Physiology of Farm Animals·View original on PubMed

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Original publication title: Molecular characterization of a canine coronavirus NA/09 strain detected in a dog's organs.

Species:
dog

Plain-English summary

A dog with severe diarrhea was found to have a strain of canine coronavirus (CCoV) in its organs. Tests confirmed the presence of this virus, which is known to cause serious illness in dogs. The researchers noted that this strain was similar to another known dangerous strain, indicating that there may be new variants of the virus emerging. Unfortunately, the dog did not survive, highlighting the potential severity of infections caused by this virus.

People also search for: dog diarrhea coronavirus · canine coronavirus symptoms · severe diarrhea in dogs

Abstract

In the present study, the detection of a pantropic canine coronavirus (CCoV) strain in a dog with lethal diarrhoea is reported. RT-PCR and real-time RT-PCR assays were used for the detection, characterization and quantitation of CCoV. Sequence and phylogenetic analysis of the CCoV NA/09 revealed a high degree of sequence identity with the pantropic strain CB/05, indicating the presence of CB/05-like pantropic strains in Greece. The absence of the 38-nucleotide deletion in ORF3b, which is characteristic of CB/05, indicates the need to identify new genetic markers for pantropic variants of CCoV, probably in the spike-protein gene region.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22002680/