Peer-reviewed veterinary case report
Molecular characterization of a Marek's disease virus strain detected in tumour-bearing turkeys.
- Journal:
- Avian pathology : journal of the W.V.P.A
- Year:
- 2020
- Authors:
- Mescolini, Giulia et al.
- Affiliation:
- Department of Veterinary Medical Sciences · Italy
Abstract
Marek's disease (MD) is a lymphoproliferative disease caused by(GaHV-2), which primarily affects chickens. However, the virus is also able to induce tumours in turkeys, albeit less frequently than in chickens. This study reports the molecular characterization of a GaHV-2 strain detected in a flock of Italian meat-type turkeys exhibiting visceral lymphomas. Sequencing and phylogenetic analysis of thegene revealed that the turkey GaHV-2 has molecular features of high virulence and genetic similarity with GaHV-2 strains recently detected in Italian commercial and backyard chickens. GaHV-2 is ubiquitous among chickens despite vaccination, and chicken-to-turkey transmission is hypothesized due to the presence of broilers in neighbouring pens.A GaHV-2 strain from Italian turkeys was molecularly characterized.The turkey strain presented molecular characteristics of high virulence in itsgene.The turkey strain was closely related to previously detected chicken strains.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31702386/