Peer-reviewed veterinary case report
Molecular characterization of Newcastle disease virus strains isolated from different outbreaks in Northeast India during 2014-15.
- Journal:
- Microbial pathogenesis
- Year:
- 2016
- Authors:
- Nath, Barnali et al.
- Affiliation:
- Department of Biosciences and Bioengineering · India
Abstract
Newcastle disease virus (NDV) isolates recovered from different outbreaks in chicken flocks in Assam during 2014-15 were genotypically and pathotypically characterized. Nucleotide sequence analysis of fusion (F) and hemagglutinin protein genes showed a close similarity with genotype XIII strains of NDV. Amino acid sequence of F protein showed a virulent cleavage site (112)R-R-Q-K-R-F(117). Furthermore, pathogenicity test in one-day-old chicks and embryonated chicken eggs showed a virulent pathotype of the isolated NDV strains. The study will help us to understand the biology of circulating strains of NDV in Northeastern part of India.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26657722/