Peer-reviewed veterinary case report
Molecular characterization of three new virulent Newcastle disease virus variants isolated in China.
- Journal:
- Journal of clinical microbiology
- Year:
- 2008
- Authors:
- Tan, Lei-Tao et al.
- Affiliation:
- Institute of Poultry Science · China
Abstract
Three cases of Newcastle disease virus (NDV) found in nature had the lentogenic motif (112)G-R-Q-G-R-L(117) in their fusion protein cleavage sites. However, both intracerebral pathogenicity and intravenous pathogenicity indexes showed that these NDV isolates were virulent. In comparison with the LaSota live virus vaccine, these viruses had significant genetic variations in the hemagglutinin-neuraminidase gene.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18057137/