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Peer-reviewed veterinary case report

Common blood infections in dogs from southern India explained

By Venugopal, Vidhya et al.·Published in Veterinary parasitology, regional studies and reports·2026·Department of Veterinary Epidemiology and Preventive Medicine, India·View original on PubMed

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Original publication title: Molecular epidemiology and phylogenetics of canine haemoprotozoan and rickettsial infections in southern India.

Species:
dog
Canine babesiosisAppetite & weightDogs

Plain-English summary

A group of dogs in southern India were found to have serious infections caused by blood parasites and bacteria, showing symptoms like fever, loss of appetite, and low platelet counts. The most common infections were from the Babesia species, with many dogs having multiple infections at once. Most affected dogs were young males, and many had ticks on them. Blood tests showed signs of anemia and other health issues. The study suggests that better testing and treatment options are needed to help these dogs and control the ticks that spread these diseases.

People also search for: dog fever and loss of appetite · tick-borne diseases in dogs · Babesia infection treatment in dogs

Abstract

Haemoprotozoan infections pose significant health risks to dogs, especially in tropical regions. This study investigated the epidemiology and molecular characteristics of Babesia gibsoni, Babesia vogeli, Hepatozoon canis, Ehrlichia canis, Anaplasma platys, and Rickettsia spp. in 120 clinically affected dogs from southern India (November 2023-September 2024). Dogs exhibiting pyrexia, anorexia, and thrombocytopenia were screened via blood smear microscopy and PCR. Babesia spp. were most prevalent (66.7 %, 80/120), with co-infections of B. gibsoni and B. vogeli (76.3 % of Babesia-positive cases) being common. In contrast, E. canis (6/120, 5.0 %), A. platys (2/120, 1.7 %), and H. canis (2/120, 1.7 %) were detected at much lower rates; no Rickettsia spp. were found. Infected dogs were more often male and typically 1-3 years old, with a peak in cases during the pre-monsoon season (March-May). Tick infestation was frequently observed among cases. Clinically, affected dogs showed fever, pallor, splenomegaly, lymphadenopathy, and dehydration. Haematological and biochemical analyses revealed anaemia, thrombocytopenia, leukocytosis, elevated ALT, ALP, and bilirubin, and reduced total protein in infected dogs. Phylogenetic analysis of the amplified 18S and 16S rRNA gene sequences showed close relationships with strains from other Asian regions. Our findings highlight the high prevalence of multi-pathogen co-infections and underscore the need for improved diagnostic, treatment, and vector-control strategies. A One Health perspective is recommended to address the zoonotic risk of these tick-borne pathogens.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41651622/