Peer-reviewed veterinary case report
Canine parvovirus infection rates in dogs in Egypt study
By Elbaz, Elzahara et al.·Published in Comparative immunology, microbiology and infectious diseases·2021·Department of Internal Medicine and Infectious Diseases·View original on PubMed →
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Original publication title: Molecular investigation on the presence of canine parvovirus in Egypt.
- Species:
- dog
Plain-English summary
A group of dogs in Egypt showed signs of severe vomiting and diarrhea, which led to testing for canine parvovirus (CPV-2), a highly contagious disease. Out of 50 dogs tested, 35 were found to be positive for the virus, with the highest rates in German shepherds and puppies under six months old. The rapid test and clinical signs were the best indicators of infection. This study highlights the prevalence of CPV-2 in the area and suggests that more research is needed to understand the virus's strains and their impact on vaccinated dogs.
People also search for: dog vomiting diarrhea parvovirus · German shepherd puppy parvovirus symptoms · canine parvovirus treatment
Abstract
Canine parvovirus type 2 (CPV-2) causes a highly contagious gastroenteritis disease of dogs and wild canids. To investigate the CPV-2 prevalence in Dakahlia Governorate, Egypt, a total of 50 fecal swabs were collected from suspected diseased dogs during 2016-2017. Out of 50 collected samples, 35 samples (70 %) presented positive results for CPV-2 using immuno-chromatography (IC) as a rapid test. CPV-2DNA was detected in 42 samples (84 %) by using polymerase chain reaction (PCR). The frequencies of CPV-2 were significantly higher in German shepherd breed (46 %; 23/50) and in age groups less than 6 months (76%; 38/50). We evaluated the breed, age, sex, rapid test results and clinical signs as predictors for classification of animal status into infected and not infected. The best predictors for classification process were rapid test result and clinical signs. Both CPV-2b and CPV-2c subtypes were detected by CPV2-VP2 gene sequences analysis. Deduced amino acid sequences alignment showed substitutions at 3 sites (Arg453Pro, Ala574Glu and Gln457Leu). Further investigations are needed to reveal the genetic and antigenic relation between field and vaccinal strains of CPV-2 in Egypt.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33285387/